Chrome //net-internals/#dns - How safe is it to flush DNS?

While reading this Google Chrome Clear or Flush the DNS Cache Tutorial - nixCraft I found the url chrome //net-internals/#dns. So how safe is it to flush DNS like this using this URL?

Yes, you can use it without any issue. Are you getting any problems?

Sometimes it still uses old DNS records. That is why I ask.

Are you using Google DNS or Cloudflare DNS? You can flush them from

AND:

https://1.1.1.1/purge-cache/

Another option is operating system level DNS that you need to flush out.